{"id":611,"date":"2023-01-26T12:06:48","date_gmt":"2023-01-26T12:06:48","guid":{"rendered":"https:\/\/grupos.eez.csic.es\/molecolab\/?page_id=611"},"modified":"2026-04-01T08:38:58","modified_gmt":"2026-04-01T08:38:58","slug":"projects","status":"publish","type":"page","link":"https:\/\/grupos.eez.csic.es\/molecolab\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd1osxh-0a1b799a2b967f3a4339c8b1dbac2ec7\">\n.avia-section.av-ldd1osxh-0a1b799a2b967f3a4339c8b1dbac2ec7 .av-parallax .av-parallax-inner{\nbackground-repeat:no-repeat;\nbackground-image:url(https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta-suelo.jpg);\nbackground-position:50% 50%;\nbackground-attachment:scroll;\n}\n.avia-section.av-ldd1osxh-0a1b799a2b967f3a4339c8b1dbac2ec7 .av-section-color-overlay{\nopacity:0.7;\nbackground-color:#323e49;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-ldd1osxh-0a1b799a2b967f3a4339c8b1dbac2ec7 main_color avia-section-huge avia-no-border-styling  avia-builder-el-0  el_before_av_hr  avia-builder-el-first  avia-full-stretch av-parallax-section avia-bg-style-parallax av-section-color-overlay-active av-minimum-height av-minimum-height-25  container_wrap sidebar_right'  data-section-bg-repeat='stretch' data-av_minimum_height_pc='25'><div class='av-parallax' data-avia-parallax-ratio='0.3' ><div class='av-parallax-inner main_color avia-full-stretch'><\/div><\/div><div class=\"av-section-color-overlay-wrap\"><div class=\"av-section-color-overlay\"><\/div><a href='#next-section' title='' class='scroll-down-link ' aria-hidden='true' data-av_icon='\ue877' data-av_iconfont='entypo-fontello'><\/a><div class='container av-section-cont-open' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-611'><div class='entry-content-wrapper clearfix'>\n<div class='flex_column av-edtu6j-afb606b29310709adbeb8b6651253cda av_one_fifth  avia-builder-el-1  el_before_av_three_fifth  avia-builder-el-first  first flex_column_div '     ><\/div><div class='flex_column av-e7vp2r-b03956b54a12fdd404e28f2efd05faf3 av_three_fifth  avia-builder-el-2  el_after_av_one_fifth  el_before_av_one_fifth  flex_column_div '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8\">\n#top .av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8{\npadding-bottom:10px;\ncolor:#ffffff;\nfont-size:40px;\n}\nbody .av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .av-special-heading-tag{\nfont-size:40px;\n}\n.av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .special-heading-inner-border{\nborder-color:#ffffff;\n}\n.av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .av-subheading{\nfont-size:15px;\n}\n\n@media only screen and (min-width: 480px) and (max-width: 767px){ \n#top #wrap_all .av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n\n@media only screen and (max-width: 479px){ \n#top #wrap_all .av-special-heading.av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 .av-special-heading-tag{\nfont-size:0.8em;\n}\n}\n<\/style>\n<div  class='av-special-heading av-ldd1pc3x-aed233dfa8343b79eb18b956a8bb60b8 av-special-heading-h1 custom-color-heading blockquote modern-quote modern-centered  avia-builder-el-3  avia-builder-el-no-sibling  av-inherit-size'><h1 class='av-special-heading-tag'  itemprop=\"headline\"  >Projects<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><\/div><div class='flex_column av-dxo7wr-36ee334ff3b73ee908e43692437b68de av_one_fifth  avia-builder-el-4  el_after_av_three_fifth  avia-builder-el-last  flex_column_div '     ><\/div>\n<\/div><\/div><\/main><!-- close content main element --><\/div><\/div><\/div><div id='after_section_1'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-611'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd3i48f-a69adabb8c4af9a443820a4aceb06e95\">\n#top .hr.hr-invisible.av-ldd3i48f-a69adabb8c4af9a443820a4aceb06e95{\nheight:10px;\n}\n<\/style>\n<div  class='hr av-ldd3i48f-a69adabb8c4af9a443820a4aceb06e95 hr-invisible  avia-builder-el-5  el_after_av_section  el_before_av_one_third  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column av-232zkj-2e9e999bd5d87c6a869106ba925120ea av_one_third  avia-builder-el-6  el_after_av_hr  el_before_av_two_third  first flex_column_div '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd49ztx-574f883bab3ebe62a19d070567debe82\">\n.avia-image-container.av-ldd49ztx-574f883bab3ebe62a19d070567debe82 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-ldd49ztx-574f883bab3ebe62a19d070567debe82 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-ldd49ztx-574f883bab3ebe62a19d070567debe82 av-styling- avia-align-center  avia-builder-el-7  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-958 avia-img-lazy-loading-not-958 avia_image ' src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/02\/mimir-101124883-281x300.jpg\" alt='' title='mimir-101124883'  height=\"300\" width=\"281\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/02\/mimir-101124883-281x300.jpg 281w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/02\/mimir-101124883.jpg 387w\" sizes=\"(max-width: 281px) 100vw, 281px\" \/><\/div><\/div><\/div><\/div>\n<div class='flex_column av-1xa1yr-cf264e1f6ebde64f70ce8a870787fa62 av_two_third  avia-builder-el-8  el_after_av_one_third  el_before_av_hr  flex_column_div '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd48l9v-90bf191078e3e0dc5c865b34bd6b584a\">\n#top .av-special-heading.av-ldd48l9v-90bf191078e3e0dc5c865b34bd6b584a{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-ldd48l9v-90bf191078e3e0dc5c865b34bd6b584a .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-ldd48l9v-90bf191078e3e0dc5c865b34bd6b584a .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-ldd48l9v-90bf191078e3e0dc5c865b34bd6b584a av-special-heading-h3  avia-builder-el-9  el_before_av_textblock  avia-builder-el-first  av-thin-font'><h3 class='av-special-heading-tag'  itemprop=\"headline\"  ><strong>MIMIR &#8211; Exploring the Molecular Imprint of Microbe-Induced Plant Resistance in Plant-Associated Communities<\/strong><\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd467sn-69aaef693c9f1e8282441a62386167a7\">\n#top .av_textblock_section.av-ldd467sn-69aaef693c9f1e8282441a62386167a7 .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-ldd467sn-69aaef693c9f1e8282441a62386167a7'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>(101124883; DOI: 10.3030\/101124883)<\/p>\n<p><strong>Funded by the European Research Council <\/strong>(2024-2029)<\/p>\n<p><strong>Understanding microbe-induced plant resistance in agroecosystems<\/strong><\/p>\n<p>Plant-beneficial microbes have the potential to enhance plant immunity against insects, a phenomenon known as microbe-induced plant resistance (MIR). In plants, this influences insect herbivores and may extend to plant-associated communities. However, current research overlooks the impact of MIR on the trophic chain. The ERC-funded MIMIR project investigates how plant MIR is transmitted and integrated into agroecosystems, opening up new avenues for research. It will use a multidisciplinary approach to address three primary challenges: understanding the molecular regulation of MIR in insect herbivores, examining how MIR extends to the third trophic level, and assessing the impact of MIR on the rhizosphere microbiome. The project provides insights into species interactions within complex systems.<\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p><strong>PI<\/strong>: Ainhoa Mart\u00ednez Medina PhD.<\/p>\n<p><strong>Further researchers<\/strong>: Iv\u00e1n Fern\u00e1ndez L\u00f3pez PhD., Francisco J. Colina Ruiz Ph.D., Ana Mar\u00eda Jimenez Jimenez PhD., Beatriz Romero Rodr\u00edguez PhD., Alegr\u00eda P\u00e9rez Guill\u00e9n MSc., Sara Comer\u00f3n Tabernero MSc., Isabel Jim\u00e9nez Romero.<\/p>\n<p><b>This project has received funding from the European Research Council (ERC) under the European Union\u2019s Horizon Europe research and innovation <\/b><b>programme<\/b><b> (grant agreement No. <\/b><b>101124883<\/b><b>).<\/b><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-971\" src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/04\/logo-european-research-council-300x129.png\" alt=\"\" width=\"214\" height=\"92\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/04\/logo-european-research-council-300x129.png 300w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/04\/logo-european-research-council.png 369w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-14y4df-88de5aae235ceb31bb6c9c8c8aee7ac7\">\n#top .hr.av-14y4df-88de5aae235ceb31bb6c9c8c8aee7ac7{\nmargin-top:10px;\nmargin-bottom:10px;\n}\n.hr.av-14y4df-88de5aae235ceb31bb6c9c8c8aee7ac7 .hr-inner{\nwidth:50px;\nborder-color:#323e49;\n}\n<\/style>\n<div  class='hr av-14y4df-88de5aae235ceb31bb6c9c8c8aee7ac7 hr-custom  avia-builder-el-11  el_after_av_two_third  el_before_av_one_third  hr-center hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p>\n<div class='flex_column av-1q1pa3-f62b416d6869524161ead8290d500d8d av_one_third  avia-builder-el-12  el_after_av_hr  el_before_av_two_third  first flex_column_div '     ><\/div>\n<div class='flex_column av-1milnv-7538d380a94ab83c6dfa6b7214f89181 av_two_third  avia-builder-el-13  el_after_av_one_third  el_before_av_hr  flex_column_div '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mm3gls8e-03663d8106ac372e6530d603b2da2400\">\n#top .av-special-heading.av-mm3gls8e-03663d8106ac372e6530d603b2da2400{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-mm3gls8e-03663d8106ac372e6530d603b2da2400 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-mm3gls8e-03663d8106ac372e6530d603b2da2400 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-mm3gls8e-03663d8106ac372e6530d603b2da2400 av-special-heading-h3  avia-builder-el-14  el_before_av_textblock  avia-builder-el-first  av-thin-font'><h3 class='av-special-heading-tag'  itemprop=\"headline\"  ><strong>FineMIR \u2013 Fine-tuned regulation of plant defenses by IR eliciting symbionts<\/strong><\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mm3go9k5-7a1d6c9424368660ae2e6b9db85ce9d9\">\n#top .av_textblock_section.av-mm3go9k5-7a1d6c9424368660ae2e6b9db85ce9d9 .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-mm3go9k5-7a1d6c9424368660ae2e6b9db85ce9d9'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>(PID2024-162058OB)<\/p>\n<p><strong>Funded by the Spanish Ministry of Science and Innovation<\/strong> (2025-2027)<\/p>\n<p>Plant-beneficial microbes have the potential to enhance plant immunity against insects, a phenomenon known as microbe-induced plant resistance (MIR). Our previous results show that MIR is an efficient tool to add to integrated pest management programs in horticulture. However, substantial knowledge gaps remain, hindering the full potential of MIR as a pest management tool. FineMIR aims to address these gaps by leveraging our previously generated omics data and established plant-microbe-insect bioassays. Our overall goal is to refine our understanding of the complex regulation of plant defenses mediated by MIR. Specifically, we will focus on key regulatory components involved in MIR onset, systemic signaling, and display, as well as its impact on herbivorous pests (second trophic level) and their natural enemies (third trophic level). By employing comprehensive bioassays and cutting-edge molecular techniques, FineMIR will provide a deeper understanding of the mechanistic basis of MIR, and its long-term impacts on herbivore pests. Ultimately, FineMIR will yield crucial insights for the optimization of MIR as a sustainable alternative to chemical pesticides, paving the way for more environmentally friendly crop protection strategies<\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p><strong>PI<\/strong>: Ainhoa Mart\u00ednez Medina PhD (PI1). Mar\u00eda Jos\u00e9 Pozo Jim\u00e9nez PhD (PI2).<\/p>\n<p><strong>Further researchers<\/strong>: Iv\u00e1n Fern\u00e1ndez L\u00f3pez PhD., Francisco J. Colina Ruiz Ph.D.<\/p>\n<p><b>Grant<\/b><b> PID2024-162058OB<\/b><b> funded by MICIU\/AEI\/ 10.13039\/501100011033 and by ERDF\/EU<\/b><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-965\" src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-300x58.jpg\" alt=\"\" width=\"300\" height=\"58\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-300x58.jpg 300w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-768x149.jpg 768w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-705x137.jpg 705w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei.jpg 815w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1eozjn-f55fd6127ca01cdc55f2e59f963ed1d2\">\n#top .hr.av-1eozjn-f55fd6127ca01cdc55f2e59f963ed1d2{\nmargin-top:10px;\nmargin-bottom:10px;\n}\n.hr.av-1eozjn-f55fd6127ca01cdc55f2e59f963ed1d2 .hr-inner{\nwidth:50px;\nborder-color:#323e49;\n}\n<\/style>\n<div  class='hr av-1eozjn-f55fd6127ca01cdc55f2e59f963ed1d2 hr-custom  avia-builder-el-16  el_after_av_two_third  el_before_av_one_third  hr-center hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p>\n<div class='flex_column av-17sp9v-7b4fe4917b3f13182e8e891a83cb2dfd av_one_third  avia-builder-el-17  el_after_av_hr  el_before_av_two_third  first flex_column_div '     ><\/div>\n<div class='flex_column av-12itmj-37d52a016337d208a61e6d5fa1cc8579 av_two_third  avia-builder-el-18  el_after_av_one_third  el_before_av_hr  flex_column_div '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mm3gqkwg-9bc566ae9eee22b317cb07fdf1b82337\">\n#top .av-special-heading.av-mm3gqkwg-9bc566ae9eee22b317cb07fdf1b82337{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-mm3gqkwg-9bc566ae9eee22b317cb07fdf1b82337 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-mm3gqkwg-9bc566ae9eee22b317cb07fdf1b82337 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-mm3gqkwg-9bc566ae9eee22b317cb07fdf1b82337 av-special-heading-h3  avia-builder-el-19  el_before_av_textblock  avia-builder-el-first  av-thin-font'><h3 class='av-special-heading-tag'  itemprop=\"headline\"  ><strong>Understanding the role of a novel HD-ZIP transcription factor in microbe-induced plant resistance to insect pests<\/strong><\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mm3gszsu-0d79077f3eff00d1cfdf28ae9d0efa85\">\n#top .av_textblock_section.av-mm3gszsu-0d79077f3eff00d1cfdf28ae9d0efa85 .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-mm3gszsu-0d79077f3eff00d1cfdf28ae9d0efa85'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>(AMMI01)<\/p>\n<p><strong>Funded by the Spanish Research Council<\/strong> (2025-2026)<\/p>\n<p>Certain beneficial soil microbes can enhance plant immunity against pests, a phenomenon known as Microbe-Induced plant Resistance (MIR). Our previous research has demonstrated that MIR is a promising biotechnological tool for integration into horticultural pest management programs. Despite significant recent advances in understanding MIR, important knowledge gaps remain, particularly regarding the molecular regulatory mechanisms underlying its function. These gaps limit the full exploitation of MIR as a sustainable pest management strategy. Through analysis of our omics datasets, we have identified a Homeodomain-Leucine Zipper (HD-Zip) transcription factor (TF) as a potentially novel component involved in regulating MIR. Interestingly, this TF is also induced in response to nitrogen (N) starvation, suggesting it may act as a convergence point between MIR and N-starvation signaling pathways. Our prior findings have shown that nutrient availability, including N levels, influences MIR. However, the molecular mechanisms linking these two processes remain unclear. We hypothesize that this HD-Zip TF is a novel regulator of MIR and functions as a key integrator of plant responses to both microbial signals and nutrient stress. The primary objective of this project is to characterize the role of this HD-Zip TF in MIR and N-starvation responses, and to uncover the molecular link between these two processes. To achieve this, we will adopt a multidisciplinary approach combining molecular biology and genomics, with insect performance bioassays under greenhouse conditions. The outcomes of this study will provide new insights into the regulation of MIR and contribute to the development of more effective, sustainable agricultural practices by optimizing the use of microbe-induced resistance.<\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p><strong>PI<\/strong>: Ainhoa Mart\u00ednez Medina PhD.<\/p>\n<p><b>Grant<\/b><b> AMMI01<\/b> <b>funded<\/b> <b>by<\/b> <b>the<\/b> <b>Spanish<\/b> <b>Research<\/b><b> Council<\/b><\/p>\n<\/div><\/section><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-xhytn-3eb22151a4d210d1177a674755160d40\">\n#top .hr.av-xhytn-3eb22151a4d210d1177a674755160d40{\nmargin-top:10px;\nmargin-bottom:10px;\n}\n.hr.av-xhytn-3eb22151a4d210d1177a674755160d40 .hr-inner{\nwidth:50px;\nborder-color:#323e49;\n}\n<\/style>\n<div  class='hr av-xhytn-3eb22151a4d210d1177a674755160d40 hr-custom  avia-builder-el-21  el_after_av_two_third  el_before_av_one_third  hr-center hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p>\n<div class='flex_column_table av-ldd4288v-bf7fbfba1e939bdca4a6207018f2931b sc-av_one_third av-equal-height-column-flextable'><div class='flex_column av-ldd4288v-bf7fbfba1e939bdca4a6207018f2931b av_one_third  avia-builder-el-22  el_after_av_hr  el_before_av_two_third  first flex_column_table_cell av-equal-height-column av-align-top '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-p80qr-3127557a8b586775fe88c86d241a1115\">\n.avia-image-container.av-p80qr-3127557a8b586775fe88c86d241a1115 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-p80qr-3127557a8b586775fe88c86d241a1115 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-p80qr-3127557a8b586775fe88c86d241a1115 av-styling- avia-align-center  avia-builder-el-23  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-681 avia-img-lazy-loading-not-681 avia_image ' src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-773x1030.jpg\" alt='' title='colecta_suelo_noPastoreo'  height=\"1030\" width=\"773\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-773x1030.jpg 773w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-225x300.jpg 225w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-768x1024.jpg 768w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-1152x1536.jpg 1152w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-1536x2048.jpg 1536w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-1125x1500.jpg 1125w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-529x705.jpg 529w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/colecta_suelo_noPastoreo-scaled.jpg 1920w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/><\/div><\/div><\/div><\/div>\n<div class='av-flex-placeholder'><\/div><div class='flex_column av-ldd44d0d-1ace5210dfde4e11b3254d73a5125f15 av_two_third  avia-builder-el-24  el_after_av_one_third  el_before_av_hr  flex_column_table_cell av-equal-height-column av-align-top '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-kwe4b-f7b358dde922b61abc1e3f5f47ab5d88\">\n#top .av-special-heading.av-kwe4b-f7b358dde922b61abc1e3f5f47ab5d88{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-kwe4b-f7b358dde922b61abc1e3f5f47ab5d88 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-kwe4b-f7b358dde922b61abc1e3f5f47ab5d88 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-kwe4b-f7b358dde922b61abc1e3f5f47ab5d88 av-special-heading-h3  avia-builder-el-25  el_before_av_textblock  avia-builder-el-first  av-thin-font'><h3 class='av-special-heading-tag'  itemprop=\"headline\"  ><strong>RESISBIOMA<\/strong> &#8211; INDUCING TOMATO RESISTANCE AGAINST INSECT PESTS BY SOIL MICROBIOME MANAGEMENT<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-4x63-d88c27dee9924a5d8fafc859af31cdba\">\n#top .av_textblock_section.av-4x63-d88c27dee9924a5d8fafc859af31cdba .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-4x63-d88c27dee9924a5d8fafc859af31cdba'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>(2022-2025)<\/p>\n<p><span lang=\"EN-US\">The overall aim of RESBIOMA is to gain knowledge on the role of the soil microbiome as a whole, instead of single species\/strains, as an integral part of the plant immune responses against insect pests. By making use of a combination of plant-microbiome-insect-based mesocosms, integrative multi-omics high-throughput techniques, plant functional genomics, and metagenomics RESBIOMA addresses (1) the impact of steering soil microbiomes on tomato resistance to herbivory; (2) the molecular mechanisms driving microbiome-induced resistance to pests in tomato and (3) the relation of microbiome-induced resistance functions with certain microbial groups.\u00a0<\/span><\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p>PI: Dra. Ainhoa Mart\u00ednez Medina<\/p>\n<p>Further researchers: Dra. Guadalupe Zitlalpopoca Hern\u00e1ndez; Pablo M. Rodr\u00edguez Blanco; Dr. Iv\u00e1n Manuel Fern\u00e1ndez L\u00f3pez; Gloria Gonz\u00e1lez Holgado.<\/p>\n<p><strong>Grant PID2021-128318OA-I00 funded by MICIU\/AEI\/ 10.13039\/501100011033 and by ERDF\/EU<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-965\" src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-300x58.jpg\" alt=\"\" width=\"300\" height=\"58\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-300x58.jpg 300w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-768x149.jpg 768w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei-705x137.jpg 705w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2026\/03\/logo-mciu-ue-ei.jpg 815w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<\/div><\/section><\/p><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-90fhf-aef6a68b3fc340ff1d85328bb7b7f1e5\">\n#top .hr.av-90fhf-aef6a68b3fc340ff1d85328bb7b7f1e5{\nmargin-top:10px;\nmargin-bottom:10px;\n}\n.hr.av-90fhf-aef6a68b3fc340ff1d85328bb7b7f1e5 .hr-inner{\nwidth:50px;\nborder-color:#323e49;\n}\n<\/style>\n<div  class='hr av-90fhf-aef6a68b3fc340ff1d85328bb7b7f1e5 hr-custom  avia-builder-el-27  el_after_av_two_third  el_before_av_one_third  hr-center hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column_table av-un67f-6cc7b38c5203d4bb889ac41f40aa5d93 sc-av_one_third av-equal-height-column-flextable'><div class='flex_column av-un67f-6cc7b38c5203d4bb889ac41f40aa5d93 av_one_third  avia-builder-el-28  el_after_av_hr  el_before_av_two_third  first flex_column_table_cell av-equal-height-column av-align-top '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2r3ln-ec7f93c50fcf361eb2ddbdf710da8140\">\n.avia-image-container.av-2r3ln-ec7f93c50fcf361eb2ddbdf710da8140 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-2r3ln-ec7f93c50fcf361eb2ddbdf710da8140 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-2r3ln-ec7f93c50fcf361eb2ddbdf710da8140 av-styling- avia-align-center  avia-builder-el-29  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-695 avia-img-lazy-loading-not-695 avia_image ' src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/red.jpg\" alt='' title='red'  height=\"704\" width=\"923\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/red.jpg 923w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/red-300x229.jpg 300w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/red-768x586.jpg 768w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/red-705x538.jpg 705w\" sizes=\"(max-width: 923px) 100vw, 923px\" \/><\/div><\/div><\/div><\/div>\n<div class='av-flex-placeholder'><\/div><div class='flex_column av-lr6wz-21c8b8ef3dd9c531dd39615bc2e09999 av_two_third  avia-builder-el-30  el_after_av_one_third  el_before_av_hr  flex_column_table_cell av-equal-height-column av-align-top '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-e2w5n-17c51dd008127b1f5de68abe3f104553\">\n#top .av-special-heading.av-e2w5n-17c51dd008127b1f5de68abe3f104553{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-e2w5n-17c51dd008127b1f5de68abe3f104553 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-e2w5n-17c51dd008127b1f5de68abe3f104553 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-e2w5n-17c51dd008127b1f5de68abe3f104553 av-special-heading-h3  avia-builder-el-31  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >DISENTANGLING THE MECHANISMS DRIVING MICROBIOME-INDUCED PEST RESISTANCE<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-7ijo3-935724e57f1918247ca1e0bc9c9dc156\">\n#top .av_textblock_section.av-7ijo3-935724e57f1918247ca1e0bc9c9dc156 .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-7ijo3-935724e57f1918247ca1e0bc9c9dc156'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" >\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1fqcr-39a0037d19dbb98e3e261ea27ef4277a\">\n#top .hr.hr-invisible.av-1fqcr-39a0037d19dbb98e3e261ea27ef4277a{\nheight:30px;\n}\n<\/style>\n<div  class='hr av-1fqcr-39a0037d19dbb98e3e261ea27ef4277a hr-invisible  avia-builder-el-33  avia-builder-el-no-sibling '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<p><strong>Funded by the Spanish National Research Council\u00a0<\/strong>(2022-2025)<\/p>\n<p><span lang=\"EN-US\">The main objective is to uncover novel key elements of the plant immune system involved in microbe-induced plant resistance (MIR) functioning in tomato; and to model tomato MIR to pests. We make use of a unique combination of integrative multi-omics high-throughput techniques, bioinformatics, functional genomics, and machine learning approaches. <\/span><\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p>PI: Dra. Ainhoa Mart\u00ednez Medina<\/p>\n<p>Further researchers: Dr. Pedro L\u00f3pez G\u00f3mez; Dr. Iv\u00e1n Manuel Fern\u00e1ndez L\u00f3pez; Gloria Gonz\u00e1lez Holgado.<\/p>\n<\/div><\/section><\/p><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-ldd4e8z9-18599c146504de4eb7781a4de8b2b211\">\n#top .hr.av-ldd4e8z9-18599c146504de4eb7781a4de8b2b211{\nmargin-top:10px;\nmargin-bottom:10px;\n}\n.hr.av-ldd4e8z9-18599c146504de4eb7781a4de8b2b211 .hr-inner{\nwidth:50px;\nborder-color:#323e49;\n}\n<\/style>\n<div  class='hr av-ldd4e8z9-18599c146504de4eb7781a4de8b2b211 hr-custom  avia-builder-el-34  el_after_av_two_third  el_before_av_one_third  hr-center hr-icon-no'><span class='hr-inner inner-border-av-border-fat'><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<div class='flex_column_table av-z4vyr-631f3687e8dd835c6ed911089a108446 sc-av_one_third av-equal-height-column-flextable'><div class='flex_column av-z4vyr-631f3687e8dd835c6ed911089a108446 av_one_third  avia-builder-el-35  el_after_av_hr  el_before_av_two_third  first flex_column_table_cell av-equal-height-column av-align-top '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-q809n-e08c45f72f6b6288de979397fe14b555\">\n.avia-image-container.av-q809n-e08c45f72f6b6288de979397fe14b555 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-q809n-e08c45f72f6b6288de979397fe14b555 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-q809n-e08c45f72f6b6288de979397fe14b555 av-styling- avia-align-center  avia-builder-el-36  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-633 avia-img-lazy-loading-not-633 avia_image ' src=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-773x1030.jpg\" alt='' title=''  height=\"1030\" width=\"773\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-773x1030.jpg 773w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-225x300.jpg 225w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-768x1024.jpg 768w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-1152x1536.jpg 1152w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-1125x1500.jpg 1125w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta-529x705.jpg 529w, https:\/\/grupos.eez.csic.es\/molecolab\/wp-content\/uploads\/2023\/01\/planta.jpg 1200w\" sizes=\"(max-width: 773px) 100vw, 773px\" \/><\/div><\/div><\/div><\/div>\n<div class='av-flex-placeholder'><\/div><div class='flex_column av-jbf6z-77fdc5047415f5e85ebaacbc4fa4ca9a av_two_third  avia-builder-el-37  el_after_av_one_third  el_before_av_hr  flex_column_table_cell av-equal-height-column av-align-top '     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-g1u63-65959cc1b57ddb0d6119e342a2579836\">\n#top .av-special-heading.av-g1u63-65959cc1b57ddb0d6119e342a2579836{\npadding-bottom:10px;\n}\nbody .av-special-heading.av-g1u63-65959cc1b57ddb0d6119e342a2579836 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-g1u63-65959cc1b57ddb0d6119e342a2579836 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-g1u63-65959cc1b57ddb0d6119e342a2579836 av-special-heading-h3  avia-builder-el-38  el_before_av_textblock  avia-builder-el-first '><h3 class='av-special-heading-tag'  itemprop=\"headline\"  >TOWARDS IDENTIFYING COMMON PATTERNS OF MICROBE-INDUCED PLANT RESISTANCE AGAINST INSECT PESTS<\/h3><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-71j0j-a1165dc59c3ec8c9c3eaa73dde710a9d\">\n#top .av_textblock_section.av-71j0j-a1165dc59c3ec8c9c3eaa73dde710a9d .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-71j0j-a1165dc59c3ec8c9c3eaa73dde710a9d'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" >\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8gqdn-c7d709157c3238033397d110ab476e4b\">\n#top .hr.hr-invisible.av-8gqdn-c7d709157c3238033397d110ab476e4b{\nheight:30px;\n}\n<\/style>\n<div  class='hr av-8gqdn-c7d709157c3238033397d110ab476e4b hr-invisible  avia-builder-el-40  avia-builder-el-no-sibling '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<p><strong>Funded by the Biotechnology and Biological Sciences Research Council\u00a0<\/strong>(2022-2026)<\/p>\n<p style=\"text-align: justify;\"><span lang=\"EN-US\">The main objective is to synthesize and integrate available \u2018omics data (at transcriptomic and metabolomic levels) among the collaboration partners to test the hypothesis that there are common plant mechanistic patterns of microbe-induced plant resistance (MIR) across multiple crops, microbes, and insect pests. <\/span><\/p>\n<blockquote>\n<p><strong>Research team<\/strong><\/p>\n<\/blockquote>\n<p>Coordinator: Dra. Sharon Zytynska (University of Liverpool)<\/p>\n<p>PIs of the Spanish Team: Dra. Ainhoa Mart\u00ednez Medina and Dra. Maria J. Pozo<\/p>\n<\/div><\/section><\/p><\/div><\/div><!--close column table wrapper. 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